Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins
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چکیده
منابع مشابه
Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins
The Ashkenazi Jewish (AJ) population is a genetic isolate close to European and Middle Eastern groups, with genetic diversity patterns conducive to disease mapping. Here we report high-depth sequencing of 128 complete genomes of AJ controls. Compared with European samples, our AJ panel has 47% more novel variants per genome and is eightfold more effective at filtering benign variants out of AJ ...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2014
ISSN: 2041-1723
DOI: 10.1038/ncomms5835